Multimodal Proton And Fluorescence Image Sensor For Bio Applications

• doi: 10.1109/VLSISoC.2011.6081603
• title: Multimodal proton and fluorescence image sensor for bio applications
• publisher: IEEE
• isbn: 978-1-4577-0169-6
• issn: 2324-8440
• partnum: 11EX5394
• rank: 3074
• access_type: LOCKED
• content_type: Conferences
• abstract: We developed a multimodal sensor for proton (pH, power of Hydrogen) and filter-less fluorescence imaging by using CMOS (complementary metal-oxide semiconductor) silicon integrated circuit technology. In the developed device, a proton sensor which uses CCD (charge-coupled device) image sensor technology and a filter-less fluorescence detection sensor are fused in the same pixel. Both pH and fluorescence images were first ever successfully obtained without optical filters or gratings and simultaneously in the same area in real time using the developed image sensor.
• article_number: 6081603
• pdf_url: https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6081603
• html_url: https://ieeexplore.ieee.org/document/6081603/
• abstract_url: https://ieeexplore.ieee.org/document/6081603/
• publication_title: 2011 IEEE/IFIP 19th International Conference on VLSI and System-on-Chip
• conference_location: Hong Kong, China
• conference_dates: 3-5 Oct. 2011
• publication_number: 6069623
• is_number: 6081592
• publication_year: 2011
• publication_date: 3-5 Oct. 2011
• start_page: 5
• end_page: 9
• citing_paper_count: 0
• citing_patent_count: 1
• download_count: 125
• insert_date: 20111117
• index_terms:
  • ieee_terms:
    • Biomedical imaging
    • Biomedical measurements
    • Computational fluid dynamics
    • Equations
    • Argon
    • Software
  • author_terms:
    • charge transfer devices
    • CMOS integrated circuit
    • pH
    • fluorescence
  • dynamic_index_terms:
    • Image Sensor
    • Camera Sensor
    • Proton Sensor
    • Fluorescence Detection
    • Sensor For Detection
    • Hydrogen Energy
    • Hydrogen Fuel
    • Multimodal Sensor
    • Optical Grating
    • Optical Diffraction Gratings
    • High-resolution
    • Electrode
    • Electrolyte
    • Electrolysis
    • Chemical Vapor Deposition
    • Vapor Deposition
    • Chemical Deposition
    • Electric Charge
    • Electrically Neutral
    • Electrostatic Charge
    • Fluorescent Light
    • Fluorescent Lamps
    • Fluorescent Tubes
    • Output Signal
    • Optical Characteristics
    • Optical Features
    • Optical Quality
    • Analog-to-digital Converter
    • Analog-to-digital
    • Digital-to-analog Converter
    • Measurement Procedure
    • Printed Circuit Board
    • Device Structure
    • Potential Well
    • Plasma-enhanced Chemical Vapor Deposition
    • PECVD
    • Real-time Fluorescence
    • Low-pressure Chemical Vapor Deposition
    • LPCVD
    • Fluorescent Sensor
    • High Time Resolution
    • Biochemical Sensors
• isbn_formats:
  • format: Online ISBN, value: 978-1-4577-0169-6, isbnType: New-2005
  • format: Print ISBN, value: 978-1-4577-0171-9, isbnType: New-2005
  • format: Electronic ISBN, value: 978-1-4577-0170-2, isbnType: New-2005
• authors:
  • Author Name: Hirokazu Nakazawa
    Affiliation: Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Japan
    Author URL: https://ieeexplore.ieee.org/author/37950282100
    ID: 37950282100
    Order: 1
    Author Affiliations:
    • Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Japan
  • Author Name: Makoto Ishida
    Affiliation: Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Japan
    Author URL: https://ieeexplore.ieee.org/author/37277543400
    ID: 37277543400
    Order: 2
    Author Affiliations:
    • Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Japan
  • Author Name: Kazuaki Sawada
    Affiliation: Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Japan
    Author URL: https://ieeexplore.ieee.org/author/37277567600
    ID: 37277567600
    Order: 3
    Author Affiliations:
    • Integrated Circuit and Sensor System Group, Toyohashi University of Technology, Toyohashi, Japan

Image Sensor

• sensor_type: CMOS
• resolution: 32x32 pixels
• dynamic_range: Not explicitly mentioned
• pixel_size: 130 µm
• dark_current: Not specifically stated

Optical Data

• focal_length: Not explicitly mentioned
• aperture: Not explicitly mentioned
• field_of_view: Not explicitly mentioned
• distortion: Not explicitly mentioned

Performance Metrics

• frame_rate: 5 frames/s
• signal_to_noise_ratio: Not explicitly mentioned
• sensitivity: 38 mV/pH
• shutter_speed: Not explicitly mentioned
• power_consumption: Not explicitly mentioned
• noise: Not explicitly mentioned

Applications & Benefits

• cell_imaging: Enabled simultaneous imaging of both pH and fluorescence in real time.
• benefits: Allows for high spatial resolution imaging of biochemical information.

Supporting Organizations

• supported_by: Global COE Program 'Frontiers of Intelligent Sensing', Hamamatsu Optoelectronics Knowledge Cluster Initiative, Japan Society for the Promotion of Science, Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT).

Manuscript Details

• publication_date: 3-5 Oct. 2011

Relevancy Score

• score: 9
• missing_fields:
  • dynamic_range
  • dark_current
  • focal_length
  • aperture
  • field_of_view
  • distortion
  • signal_to_noise_ratio
  • shutter_speed
  • power_consumption
  • noise

Processed JSON Filename

request_33c5b4ea-5d7a-4e02-9a96-2dc37bdb28ad-multimodal_proton_and_fluorescence_image_sensor_for_bio_applications.json