Molecular Diagnostics Based On Smart Phone

• doi: 10.1109/ICTC.2011.6082622
• title: Molecular diagnostics based on smart phone
• publisher: IEEE
• isbn: 978-1-4577-1266-1
• issn: 2162-1241
• partnum: 11EX5682
• rank: 3036
• access_type: LOCKED
• content_type: Conferences
• abstract: This study shows a valuable impact of the complementary metal oxide semi conductor (CMOS) image sensor and indium nanoparticle (InNP) substrates used for the detection of antigen-antibody interactions. Dielectric layer of antigen-antibodies bind on the conducting metal surface, which is helpful for the scattering of electro magnetic radiation. Different types of antigens such as Interferon Gamma, C-reactive protein and Troponin I were adsorbed on the InNP substrate and interact with specific antibodies. The antigen-antibody detection was based on the photon count measurements before and after protein binding observed by CMOS image sensor, which is converted into digital form with the help of analog to digital converter (ADC). Various thickness of InNP substrates were analyzed for antigen-antibody interaction. The photon counts gradually decrease when subsequent protein layers adsorbed on the substrates. This photon number is directly proportional to the digital number observed with the CMOS sensor for detecting antigen-antibody interactions.
• article_number: 6082622
• pdf_url: https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6082622
• html_url: https://ieeexplore.ieee.org/document/6082622/
• abstract_url: https://ieeexplore.ieee.org/document/6082622/
• publication_title: ICTC 2011
• conference_location: Seoul, Korea (South)
• conference_dates: 28-30 Sept. 2011
• publication_number: 6069691
• is_number: 6082527
• publication_year: 2011
• publication_date: 28-30 Sept. 2011
• start_page: 383
• end_page: 387
• citing_paper_count: 1
• citing_patent_count: 0
• download_count: 141
• insert_date: 20111117
• index_terms:
  • ieee_terms:
    • Substrates
    • Photonics
    • Proteins
    • CMOS integrated circuits
    • CMOS image sensors
    • Immune system
    • Protein engineering
  • author_terms:
    • CMOS image sensor
    • Nanoparticle
    • Immunoassay
    • Smart phone
  • dynamic_index_terms:
    • C-reactive Protein
    • Inflammatory Markers
    • Specific Antibodies
    • Troponin
    • Troponin I
    • Analog-to-digital Converter
    • Analog-to-digital
    • Digital-to-analog Converter
    • Image Sensor
    • Camera Sensor
    • Metal Oxide Semiconductor
    • Photon Counting
    • Digital Format
    • Detection Of Interactions
    • Substrate Thickness
    • Protein Layer
    • Antibody-antigen Interactions
    • Antigen-antibody Interaction
    • Electrical Energy
    • Respective Antibodies
    • Secondary Ab
    • Non-specific Adsorption
    • Markers Of Cardiovascular Disease
    • Specific Adsorption
    • Primary Abs
    • Ab Binding
    • Aβ Binding
    • Binding Of Abs
    • Cardiovascular Markers
• isbn_formats:
  • format: CD, value: 978-1-4577-1266-1, isbnType: New-2005
  • format: Print ISBN, value: 978-1-4577-1267-8, isbnType: New-2005
  • format: Electronic ISBN, value: 978-1-4577-1268-5, isbnType: New-2005
• authors:
  • Author Name: Jasmine Pramila Devadhasan
    Affiliation: College of Bionanotechnology, Kyungwon University, Seongnam, Gyeonggi, South Korea
    Author URL: https://ieeexplore.ieee.org/author/38230439400
    ID: 38230439400
    Order: 1
    Author Affiliations:
    • College of Bionanotechnology, Kyungwon University, Seongnam, Gyeonggi, South Korea
  • Author Name: Mohana Marimuthu
    Affiliation: College of Bionanotechnology, Kyungwon University, Seongnam, Gyeonggi, South Korea
    Author URL: https://ieeexplore.ieee.org/author/37088314109
    ID: 37088314109
    Order: 2
    Author Affiliations:
    • College of Bionanotechnology, Kyungwon University, Seongnam, Gyeonggi, South Korea
  • Author Name: Sanghyo Kim
    Affiliation: College of Bionanotechnology, Kyungwon University, Seongnam, Gyeonggi, South Korea
    Author URL: https://ieeexplore.ieee.org/author/37089078173
    ID: 37089078173
    Order: 3
    Author Affiliations:
    • College of Bionanotechnology, Kyungwon University, Seongnam, Gyeonggi, South Korea

Image Sensor

• sensor_type: CMOS
• resolution: 376x314
• dynamic_range: Not specified
• pixel_size: Not specified
• dark_current: Not specified

Optical Data

• focal_length: Not specified
• aperture: Not specified
• field_of_view: Not specified
• distortion: Not specified

Performance Metrics

Applications & Benefits

• cell_imaging: Used for antigen-antibody interaction detection and other biomedical applications.
• benefits: Low power consumption, portability, cost-effective for immunodetection, high sensitivity.

Supporting Organizations

• supported_by: Korean Ministry of Education & Science Technology; Ministry of Knowledge Economy (MKE, Korea)

Manuscript Details

• publication_date: 28-30 Sept. 2011

Relevancy Score

• score: 9
• missing_fields:
  • dynamic_range
  • pixel_size
  • dark_current
  • focal_length
  • aperture
  • field_of_view
  • distortion
  • frame_rate
  • signal_to_noise_ratio
  • sensitivity
  • shutter_speed
  • power_consumption
  • noise

Processed JSON Filename

request_26db678b-0f13-449f-8e51-cbcc37577151-molecular_diagnostics_based_on_smart_phone.json