Miniaturized Broadband Microwave Permittivity Sensing For Biomedical Applications

• doi: 10.1109/JERM.2018.2882564
• title: Miniaturized Broadband Microwave Permittivity Sensing for Biomedical Applications
• publisher: IEEE
• isbn:
• issn: 2469-7257
• rank: 3011
• access_type: LOCKED
• content_type: Journals
• abstract: We present a compact, scalable, and broadband architecture for the implementation of complex microwave permittivity sensors in complementary metal-oxide semiconductor (CMOS) technology. The proposed architecture consists of a patch sensor embedded in a programmable balanced readout bridge and performs third and fifth harmonic downconversion for fast multifrequency readout. Circuits designed can act as the basic building block for a wide span of biomedical applications, ranging from wearables to permittivity imaging. Experimental results of manufactured prototypes demonstrate measurement noise reduction through bridge balancing, Debye model parameter estimation of independent material with a 1.6% error using full frequency dataset, and 5.3% in high energy efficiency mode, as well as image construction based on material permittivity differences.
• article_number: 8542742
• pdf_url: https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=8542742
• html_url: https://ieeexplore.ieee.org/document/8542742/
• abstract_url: https://ieeexplore.ieee.org/document/8542742/
• publication_title: IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology
• conference_location:
• conference_dates:
• publication_number: 7397573
• is_number: 8645735
• publication_year: 2019
• publication_date: March 2019
• start_page: 48
• end_page: 55
• citing_paper_count: 11
• citing_patent_count: 0
• download_count: 972
• insert_date: 20181121
• index_terms:
  • ieee_terms:
    • Sensors
    • Permittivity
    • Bridge circuits
    • Radio frequency
    • Permittivity measurement
    • Metals
    • Microwave circuits
  • author_terms:
    • Bridge circuits
    • biomedical sensors
    • complementary metal-oxide semiconductor (CMOS) sensors
    • complex permittivity measurement
    • microwave sensors
  • dynamic_index_terms:
    • Microwave Permittivity
    • Energy Efficiency
    • Measurement Noise
    • Circuit Design
    • Debye Temperature
    • Debye Theory
    • Debye Model
    • Complementary Metal Oxide Semiconductor Technology
    • Complementary Metal-oxide-semiconductor Technology
    • Frequency Range
    • Measurement Time
    • Power Consumption
    • Fast Fourier Transform
    • Inverse Fast Fourier Transform
    • Fundamental Frequency
    • Natural Frequency
    • Imaginary Part
    • Analog-to-digital Converter
    • Analog-to-digital
    • Digital-to-analog Converter
    • Ground Plane
    • Floor Plan
    • Dielectric Function
    • Complex Permittivity
    • Frequency Points
    • Single Chip
    • Permittivity Values
    • Real Part Of Permittivity
    • Imaginary Part Of Permittivity
    • Permittivity Measurements
    • Output Pixel
    • Reference Path
    • Removal Surgery
    • Readout Circuit
    • Configuration Matrix
    • Configuration Matrices
• authors:
  • Author Name: Gerasimos Vlachogiannakis
    Affiliation: Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
    Author URL: https://ieeexplore.ieee.org/author/37085423918
    ID: 37085423918
    Order: 1
    Author Affiliations:
    • Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
  • Author Name: Zhebin Hu
    Affiliation: Delft University of Technology, Delft, The Netherlands
    Author URL: https://ieeexplore.ieee.org/author/37086152921
    ID: 37086152921
    Order: 2
    Author Affiliations:
    • Delft University of Technology, Delft, The Netherlands
  • Author Name: Harshitha Thippur Shivamurthy
    Affiliation: Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
    Author URL: https://ieeexplore.ieee.org/author/37085401806
    ID: 37085401806
    Order: 3
    Author Affiliations:
    • Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
  • Author Name: Andrea Neto
    Affiliation: Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
    Author URL: https://ieeexplore.ieee.org/author/37277414700
    ID: 37277414700
    Order: 4
    Author Affiliations:
    • Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
  • Author Name: Michiel A. P. Pertijs
    Affiliation: Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
    Author URL: https://ieeexplore.ieee.org/author/37268706100
    ID: 37268706100
    Order: 5
    Author Affiliations:
    • Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
  • Author Name: Leo C. N. de Vreede
    Affiliation: Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
    Author URL: https://ieeexplore.ieee.org/author/37275706300
    ID: 37275706300
    Order: 6
    Author Affiliations:
    • Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
  • Author Name: Marco Spirito
    Affiliation: Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands
    Author URL: https://ieeexplore.ieee.org/author/38515027800
    ID: 38515027800
    Order: 7
    Author Affiliations:
    • Department of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, The Netherlands

Image Sensor

• sensor_type: CMOS
• resolution: 150 × 300 μm2
• dynamic_range: Not specified
• pixel_size: 100 × 100 μm
• dark_current: Not specified

Optical Data

• focal_length: Not specified
• aperture: Not specified
• field_of_view: Not specified
• distortion: Not specified

Performance Metrics

• power_consumption: Between 1.2 mW at 0.1 GHz and 24 mW at 5 GHz
• noise: Real part standard deviation reduced by 70%, imaginary part reduced by 95% with balanced bridge

Applications & Benefits

• cell_imaging: In-vivo tissue hydration monitoring, label-free malignant tissue inspection, drug penetration evaluation, blood glucose monitoring.
• benefits: Compact, scalable, and broadband imaging capability across biomedical applications.

Supporting Organizations

• supported_by: Dutch Technology Foundation (STW/NWO)

Manuscript Details

• publication_date: March 2019

Relevancy Score

• score: 7
• missing_fields:
  • fill factor
  • quantum efficiency
  • readout speed
  • temporal noise
  • fixed-pattern noise
  • analog-to-digital conversion techniques
  • microlenses
  • on-chip colour filters
  • global rolling shutters
  • backside illumination

Processed JSON Filename

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