Gigapixel Imaging On A Chip High Numerical Aperture Lensfree Microscopy Over A Wide Fieldofview

• doi: 10.1109/ISBI.2013.6556544
• title: Giga-pixel imaging on a chip: High numerical aperture lensfree microscopy over a wide field-of-view
• publisher: IEEE
• isbn: 978-1-4673-6454-6
• issn: 1945-8452
• partnum: 13EX8129
• rank: 2545
• access_type: LOCKED
• content_type: Conferences
• abstract: We report an on-chip lensfree holographic microscope with a large field-of-view (FOV) of ~20.5 mm2 and a high numerical aperture (NA) of ~0.9. By implementing a pixel super-resolution technique on a color CMOS image sensor, this computational microscope achieves a spatial resolution of ~300 nm at an illumination wavelength of 530 nm, yielding approximately one billion useful pixels in both the reconstructed amplitude and phase images. This lensfree holographic on-chip imaging technique can be used as the building block for high resolution, compact and cost-effective optical microscopes for various biomedical imaging applications.
• article_number: 6556544
• pdf_url: https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6556544
• html_url: https://ieeexplore.ieee.org/document/6556544/
• abstract_url: https://ieeexplore.ieee.org/document/6556544/
• publication_title: 2013 IEEE 10th International Symposium on Biomedical Imaging
• conference_location: San Francisco, CA, USA
• conference_dates: 7-11 April 2013
• publication_number: 6548349
• is_number: 6556393
• publication_year: 2013
• publication_date: 7-11 April 2013
• start_page: 592
• end_page: 595
• citing_paper_count: 0
• citing_patent_count: 0
• download_count: 230
• insert_date: 20130715
• index_terms:
  • ieee_terms:
    • Microscopy
    • Optical microscopy
    • Spatial resolution
    • Image sensors
    • Sensors
  • author_terms:
    • lensfree imaging
    • on-chip imaging
    • pixel super-resolution
    • holographic microscopy
    • in-line holography
    • giga-pixel microscopy
  • dynamic_index_terms:
    • Numerical Aperture
    • High Numerical Aperture
    • Field Of View
    • Imaging Techniques
    • Phase Contrast
    • Phase Images
    • Image Sensor
    • Camera Sensor
    • Amplitude Images
    • Holographic Images
    • Holographic Microscopy
    • Red Blood Cells
    • Erythrocytes
    • Erythroid
    • Light Source
    • Human Blood
    • Linewidth
    • Glass Substrate
    • Color Images
    • Focused Ion Beam
    • Air Gap
    • Sensor Array
    • Sub-pixel
    • Imaging Setup
    • Imaging Apparatus
    • Pixel Shift
    • Small Pixel Size
    • Color Filter
    • Mobile Camera
    • Mobile Phone Camera
    • Cell Phone Camera
    • Sensor Plane
    • Sub-pixel Resolution
    • Spatial Artifacts
    • Spatial Artefacts
    • Angular Spectrum
    • Test Chart
    • Background Illumination
• isbn_formats:
  • format: CD, value: 978-1-4673-6454-6, isbnType: New-2005
  • format: Print ISBN, value: 978-1-4673-6456-0, isbnType: New-2005
  • format: Electronic ISBN, value: 978-1-4673-6455-3, isbnType: New-2005
• authors:
  • Author Name: Wei Luo
    Affiliation: Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Author URL: https://ieeexplore.ieee.org/author/37071734800
    ID: 37071734800
    Order: 1
    Author Affiliations:
    • Electrical Engineering Department, University of California, Los Angeles, CA, USA
  • Author Name: Alon Greenbaum
    Affiliation: Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Author URL: https://ieeexplore.ieee.org/author/38489050300
    ID: 38489050300
    Order: 2
    Author Affiliations:
    • Electrical Engineering Department, University of California, Los Angeles, CA, USA
  • Author Name: Aydogan Ozcan
    Affiliation: Electrical Engineering Department, Bioengineering Department, California NanoSystems Institute, University of California, Los Angeles, CA, USA
    Author URL: https://ieeexplore.ieee.org/author/37271805000
    ID: 37271805000
    Order: 3
    Author Affiliations:
    • Electrical Engineering Department, Bioengineering Department, California NanoSystems Institute, University of California, Los Angeles, CA, USA

Image Sensor

• sensor_type: CMOS
• resolution: N/A
• dynamic_range: N/A
• pixel_size: 1.12 µm
• dark_current: N/A

Optical Data

• focal_length: N/A
• aperture: N/A
• field_of_view: 20.5 mm²
• distortion: N/A

Performance Metrics

• frame_rate: N/A
• signal_to_noise_ratio: N/A
• sensitivity: N/A
• shutter_speed: N/A
• power_consumption: N/A
• noise: N/A

Applications & Benefits

• cell_imaging: High-resolution, compact optical microscopy for biomedical applications such as blood analysis and cell tracking.
• benefits: Cost-effective, compact design eliminates the need for bulky lenses.

Supporting Organizations

• supported_by: National Science Foundation (NSF), Army Research Office (ARO), Office of Naval Research (ONR), National Institutes of Health (NIH).

Manuscript Details

• publication_date: 7-11 April 2013

Relevancy Score

• score: 10
• missing_fields:
  • resolution
  • dynamic_range
  • dark_current
  • focal_length
  • aperture
  • distortion
  • frame_rate
  • signal_to_noise_ratio
  • sensitivity
  • shutter_speed
  • power_consumption
  • noise

Processed JSON Filename

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