A Secondgeneration Imaging System For Freely Moving Animals

• doi: 10.1109/ISCAS.2012.6271408
• title: A second-generation imaging system for freely moving animals
• publisher: IEEE
• isbn: 978-1-4673-0217-3
• issn: 0271-4302
• partnum: 12CH38929
• rank: 1272
• access_type: LOCKED
• content_type: Conferences
• abstract: An updated image sensor to be used in a miniature microscope system for recording brain activity over a wide cortical area (4–9 mm2) is presented. The image sensor is a 100 × 100 pixel array fabricated in bulk CMOS process. The sensor also contains a 10-bit ADC and two input channels to measure other physiological signals concurrently with the optical data. Another feature of the image sensor is the ability to observe dF over sequential frames in hardware, in order to reduce the amount of data that must be read out of the image sensor at high speeds. The speed and noise performance of the image sensor is suitable for voltage-sensitive optical probes in small systems for awake and freely moving animals.
• article_number: 6271408
• pdf_url: https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6271408
• html_url: https://ieeexplore.ieee.org/document/6271408/
• abstract_url: https://ieeexplore.ieee.org/document/6271408/
• publication_title: 2012 IEEE International Symposium on Circuits and Systems (ISCAS)
• conference_location: Seoul, Korea (South)
• conference_dates: 20-23 May 2012
• publication_number: 6257548
• is_number: 6270389
• publication_year: 2012
• publication_date: 20-23 May 2012
• start_page: 105
• end_page: 108
• citing_paper_count: 0
• citing_patent_count: 0
• download_count: 119
• insert_date: 20120820
• index_terms:
  • ieee_terms:
    • Image sensors
    • Animals
    • Optical imaging
    • Biomedical optical imaging
    • High speed optical techniques
    • Optical recording
  • dynamic_index_terms:
    • Imaging System
    • Image Sensor
    • Camera Sensor
    • Sequence Of Frames
    • Optical Probe
    • Optical Investigations
    • High-resolution
    • Volume Change
    • Changes In Intensity
    • Storage Capacity
    • Current Voltage
    • Temporal Differences
    • Temporal Deviation
    • Sine Wave
    • Change In Fluorescence Intensity
    • Neural Recordings
    • Output Line
    • Reset Voltage
• isbn_formats:
  • format: CD, value: 978-1-4673-0217-3, isbnType: New-2005
  • format: Print ISBN, value: 978-1-4673-0218-0, isbnType: New-2005
  • format: Electronic ISBN, value: 978-1-4673-0219-7, isbnType: New-2005
• authors:
  • Author Name: Joon Hyuk Park
    Affiliation: Department of Electrical Engineering, Yale University, USA
    Author URL: https://ieeexplore.ieee.org/author/37579117100
    ID: 37579117100
    Order: 1
    Author Affiliations:
    • Department of Electrical Engineering, Yale University, USA
  • Author Name: Jelena Platisa
    Affiliation: John B. Pierce Laboratory, Yale University, USA
    Author URL: https://ieeexplore.ieee.org/author/38522883700
    ID: 38522883700
    Order: 2
    Author Affiliations:
    • John B. Pierce Laboratory, Yale University, USA
  • Author Name: Vincent Pieribone
    Affiliation: John B. Pierce Laboratory, Department of Cellular and Molecular Physiology, Yale University, USA
    Author URL: https://ieeexplore.ieee.org/author/37569271900
    ID: 37569271900
    Order: 3
    Author Affiliations:
    • John B. Pierce Laboratory, Department of Cellular and Molecular Physiology, Yale University, USA
  • Author Name: Eugenio Culurciello
    Affiliation: Department of Biomedical Engineering, Purdue University, USA
    Author URL: https://ieeexplore.ieee.org/author/37268496400
    ID: 37268496400
    Order: 4
    Author Affiliations:
    • Department of Biomedical Engineering, Purdue University, USA

Image Sensor

• sensor_type: CMOS
• resolution: 100x100 pixels
• dynamic_range: 54 dB
• pixel_size: 30 µm x 30 µm
• dark_current: not specified

Optical Data

• focal_length: not specified
• aperture: not specified
• field_of_view: not specified
• distortion: not specified

Performance Metrics

• frame_rate: 500 fps
• signal_to_noise_ratio: 54 dB
• noise: 3.9 mV at near saturation

Applications & Benefits

• cell_imaging: The system is designed for neural recordings using genetically encoded optical probes in freely moving animals.
• benefits: High speed, high sensitivity, and reduced data throughput.

Supporting Organizations

• supported_by: ONR (Office of Naval Research), ARO (Army Research Office)

Manuscript Details

• publication_date: 20-23 May 2012

Relevancy Score

• score: 9
• missing_fields:
  • focal_length
  • aperture
  • field_of_view
  • distortion
  • sensitivity
  • shutter_speed
  • power_consumption

Processed JSON Filename

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