A High Timeresolution Twotap Cmos Lockin Pixel Image Sensor For Timeresolved Measurements And Its Applications

• doi: 10.1109/BioCAS.2016.7833831
• title: A high time-resolution two-tap CMOS lock-in pixel image sensor for time-resolved measurements and its applications
• publisher: IEEE
• isbn: 978-1-5090-2960-0
• issn:
• rank: 1094
• access_type: LOCKED
• content_type: Conferences
• abstract: A CMOS lock-in pixel image sensor with embedded storage diodes in a pixel and lateral electric field modulator (LEFM) is developed for time-resolved measurements such as a fluorescence lifetime imaging microscopy (FLIM) and near-infrared spectroscopy (NIRS). The time-resolved CMOS image sensor (CIS) with two-tap lock-in pixels achieves a very high time resolution of 10ps when images are averaged over 30 frames, a very short intrinsic response time of 180ps at 374nm, and a low temporal random noise of 1.75e-rms with true correlated double sampling (CDS) operation. In addition, by using the LEFM and optimized process, a very high extinction ratio of approximately 94% at 472nm laser diode is achieved. The usefulness of the proposed CIS is demonstrated by the device simulations and the measurements. Then, we confirmed that the developed imager is very suitable for the scientific applications such as a biomedical imaging and multifunctional cameras.
• article_number: 7833831
• pdf_url: https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7833831
• html_url: https://ieeexplore.ieee.org/document/7833831/
• abstract_url: https://ieeexplore.ieee.org/document/7833831/
• publication_title: 2016 IEEE Biomedical Circuits and Systems Conference (BioCAS)
• conference_location: Shanghai, China
• conference_dates: 17-19 Oct. 2016
• publication_number: 7803480
• is_number: 7833706
• publication_year: 2016
• publication_date: 17-19 Oct. 2016
• start_page: 460
• end_page: 463
• citing_paper_count: 2
• citing_patent_count: 0
• download_count: 534
• insert_date: 20170126
• index_terms:
  • ieee_terms:
    • Fluorescence
    • Modulation
    • Logic gates
    • Electric fields
    • Image resolution
    • Image sensors
  • author_terms:
    • CMOS image sensor (CIS)
    • fluorecence lifetime imaging microscopy (FLIM)
    • near-infrared spectroscopy (NIRS)
    • high time-resolution
    • 2-tap lock-in pixel
  • dynamic_index_terms:
    • Image Sensor
    • Camera Sensor
    • High Time Resolution
    • Time-resolved Measurements
    • High Pixel
    • Medical Imaging
    • Clinical Imaging
    • Diagnostic Imaging
    • Time Resolution
    • Diode Laser
    • Near-infrared Spectroscopy
    • Near-infrared Spectra
    • Low Noise
    • Fluorescence Lifetime
    • Intrinsic Reaction
    • Intrinsic Response
    • Short Response Time
    • Fluorescence Lifetime Imaging Microscopy
    • FLIM
    • Fluorescence Lifetime Imaging
    • Lateral Field
    • Intrinsic Time
    • Time-resolved Imaging
    • Temporal Noise
    • Low Voltage
    • Analog-to-digital Converter
    • Analog-to-digital
    • Digital-to-analog Converter
    • Photomultiplier Tube
    • PIN Photodiode
    • Time-correlated Single-photon Counting
    • TCSPC
    • Gate Set
    • Single Electron Transfer
    • Chinese Hamster Ovary
    • Pixel Array
    • Near-infrared Spectroscopy Measurements
    • Imaging Device
    • Readout Circuit
    • Total Exposure Time
• isbn_formats:
  • format: Print on Demand(PoD) ISBN, value: 978-1-5090-2960-0, isbnType: New-2005
  • format: Electronic ISBN, value: 978-1-5090-2959-4, isbnType: New-2005
• authors:
  • Author Name: Min-Woong Seo
    Affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
    Author URL: https://ieeexplore.ieee.org/author/38063173500
    ID: 38063173500
    Order: 1
    Author Affiliations:
    • Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
  • Author Name: Yuya Shirakawa
    Affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
    Author URL: https://ieeexplore.ieee.org/author/37085993272
    ID: 37085993272
    Order: 2
    Author Affiliations:
    • Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
  • Author Name: Keiichiro Kagawa
    Affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
    Author URL: https://ieeexplore.ieee.org/author/37278023200
    ID: 37278023200
    Order: 3
    Author Affiliations:
    • Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
  • Author Name: Keita Yasutomi
    Affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
    Author URL: https://ieeexplore.ieee.org/author/37680557800
    ID: 37680557800
    Order: 4
    Author Affiliations:
    • Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
  • Author Name: Yoshimasa Kawata
    Affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
    Author URL: https://ieeexplore.ieee.org/author/37284493400
    ID: 37284493400
    Order: 5
    Author Affiliations:
    • Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
  • Author Name: Nobukazu Teranishi
    Affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
    Author URL: https://ieeexplore.ieee.org/author/37351891200
    ID: 37351891200
    Order: 6
    Author Affiliations:
    • Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
  • Author Name: Shoji Kawahito
    Affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan
    Author URL: https://ieeexplore.ieee.org/author/37300195700
    ID: 37300195700
    Order: 7
    Author Affiliations:
    • Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan

Image Sensor

• sensor_type: CMOS
• resolution: not specified
• dynamic_range: not specified
• pixel_size: not specified
• dark_current: not specified

Optical Data

• focal_length: not specified
• aperture: not specified
• field_of_view: not specified
• distortion: not specified

Performance Metrics

• noise: 1.75e-rms

Applications & Benefits

• cell_imaging: Fluorescence lifetime imaging microscopy (FLIM) and near-infrared spectroscopy (NIRS) applications, including biomedical imaging and multifunctional cameras.
• benefits: High time-resolution, low noise, very short intrinsic response time, and good performance for measuring fluorescence lifetime.

Supporting Organizations

• supported_by: Ministry of Education, Culture, Sports, Science and Technology (MEXT), MEXT/JST COI-STREAM program.

Manuscript Details

• publication_date: 17-19 Oct. 2016

Relevancy Score

• score: 10
• missing_fields:
  • resolution
  • dynamic_range
  • pixel_size
  • dark_current
  • focal_length
  • aperture
  • field_of_view
  • distortion
  • frame_rate
  • signal_to_noise_ratio
  • sensitivity
  • shutter_speed
  • power_consumption

Processed JSON Filename

request_18ea42cb-ad86-42c9-84d6-0238137c5641-a_high_timeresolution_twotap_cmos_lockin_pixel_image_sensor_for_timeresolved_measurements_and_its_applications.json